Karen Louise Sims (née Hampel), 79, passed away peacefully on Friday, July 12, 2025, at Delmar Gardens Creve Coeur. She was born on September 10, 1945, in Berwick, Pennsylvania.

Karen was preceded in death by her husband, Gary Sims; her father, Richard P. Hampel; her mother, Katherine D. Hampel; and her brother, Phillip Hampel.

She is survived by her son, Erik Sims (Tina); her grandson, Nathan Sims (Taylor); and her great-grandchildren, Luca and Emily. She also leaves behind her sisters, Paula Jones (the late Tim Jones) and Starr Himmel (Steve), as well as many nieces and nephews.

Karen dedicated over 30 years of her career to Monsanto before retiring. Outside of her professional life, she was a passionate dog enthusiast, serving for many years on the board of the Colonial Rottweiler Club and becoming an AKC Rottweiler show judge. She also enjoyed scrapbooking and was an avid football fan.

In lieu of flowers, the family requests donations be made to Stray Rescue of St. Louis.

A celebration of Karen’s life will be held at a later date.